Here we follow a process efficiency matrix that allows us to zero in on
the right atom efficiency by comparing various factors such as the right yield, maximum cost benefit and the amount
of solvent and water being used or wasted. |
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This step involves deciding the best solvent, the best catalyst and the best reagents for the reaction. It also includes optimising the reaction temperature. |
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The target of this stage is to achieve a minimum 90% yield. |
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This final step decides how green
the final product will be through a parameter called the e-factor, which decides the amount of waste generated per kilogram of product. Currently the pharmaceutical industry produces 50kg of waste for one kilogram of product. At Dr. Reddy's, we are in the process of setting an industry benchmark of cutting the wastage down to 20-25 kg per kilogram of product. |
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